Symptoms of Sickle cell crisis

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The Crisis can be divided into 4 sub types, as following:

TYPE/DESCRIPTION
SYMPTOMS
Vaso-occlusive crisis: Most common type; usually appears after age 5; the result of sickling in the microcirculation that leads to vasospasm, thrombosis, and local infection
Severe pain: Joint, abdominal, muscle, and thoracic; jaundice; dark urine; fever; elevated white blood cell (WBC) count; lethargy; fatigue; sleepiness
Sequestration crisis: Occurs in infants between 8 and 24 mo; massive pooling of RBCs in the liver and spleen
Lethargy, pale skin, hypovolemia, tachycardia, cool extremities, dropping urinary output, delayed capillary refill
Aplastic crisis: Results from bone marrow depression and is associated with viral infections; leads to compensatory increase in RBCs and RBC lysis
Lethargy, pale skin, shortness of breath, altered mental status, sleepiness
Hyperhemolytic crisis: Rare; result of certain medications or infections
Abdominal distension, jaundice, dark urine
Sickle cell crisis may be preceded by a recent infection or a stressor such as dehydration, strenuous activity, or high altitude. Other assessment findings include changes in mental status, such as sleepiness, listlessness, and irritability. Fever; severe pain; bloody urine; and pallor of the lips, tongue, palms, and nails may also occur.

Reference: Diseases and Disorders : A nursing Therapeutic Manual(14.0.6 version), F.A. Davis Company.


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notes.nursium.com: Symptoms of Sickle cell crisis
Symptoms of Sickle cell crisis
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