Pharmacology Mnemonics part 2

Pharmacology Mnemonics

Parasympathetic vs. sympathetic neurotransmitters "No sympathy for a Pair of Aces":

Norepinephren is secreted in by the

Sympathetic nervous system while

Acetylcholine is secreted in the

Parasympathetic nervous system.

 Drugs undergoing complete first pass metabolism when taken orally

'F I L T Hy'

First pass metabolism

Isoprenaline

Lignocaine

Testosterone

Hydrocortisone

Adrenoceptors: vasomotor function of alpha vs. beta ABCD:

Alpha = Constrict. Beta = Dilate.

Beta 1 selective blockers "BEAM ONE up, Scotty": Beta 1 blockers:

Esmolol

Atenolol

Metropolol

Opiods: mu receptor effects "MD CARES":

Miosis

Dependency

Constipation

Analgesics

Respiratory depression

Euphoria

Sedation

Cancer drugs: time of action between DNA->mRNA ABCDEF:

Alkylating agents

Bleomycin

Cisplastin

Dactinomycin/ Doxorubicin

Etoposide

Flutamide and other steroids or their antagonists (eg tamoxifen, leuprolide)

Tricyclic antidepressants: members worth knowing "I have to hide, the CIA is after me":

Clomipramine

Imipramine

Amitrptyline · If want the next 3 worth knowing, the DND is also after me: Desipramine

Norrtriptyline Doxepin

Asthma drugs: leukotriene inhibitor action zAfirlukast: Antagonist of lipoxygenase zIlueton: Inhibitor of LT receptor

Torsades de Pointes: drugs causing APACHE:
Amiodarone

Procainamide

Arsenium

Cisapride

Haloperidol

Eritromycin

Serotonin syndrome: components Causes HARM:

Hyperthermia

Autonomic instability (delirium)

Rigidity

Myoclonus

Beta blockers: B1 selective vs. B1B2 non-selective
A through N: B1 selective: Acebutalol, Atenolol, Esmolol, Metoprolol.

O through Z: B1, B2 nonselective:Pindolol, Propanolol, Timolol.

HMG-CoA reductase inhibitors (statins): side effects, contraindications, interactions HMG-CoA: · Side effects:

Hepatotoxicity

Myositis [aka rhabdomyolysis] · Contraindications:

Girl during pregnancy/ Growing children · Interactions:

Coumarin/ Cyclosporine

Therapeutic index: formula TILE: TI = LD50 / ED50

Antirheumatic agents (disease modifying): members CHAMP:

Cyclophosphamide

Hydroxycloroquine and choloroquinine

Auranofin and other gold compounds

Methotrexate

Penicillamine

Auranofin, aurothioglucose: category and indication Aurum is latin for "gold" (gold's chemical symbol is Au). Generic Aur- drugs (Auranofin, Aurothioglucose) are gold compounds.

· If didn't learn yet that gold's indication is rheumatoid arthritis, AUR- Acts Upon Rheumatoid.

Antiarrhythmics: class III members BIAS:

Bretylium

Ibutilide

Amiodarone Sotalol

MAOIs: indications MAOI'S:

Melancholic [classic name for atypical depression]

Anxiety

Obesity disorders [anorexia, bulemia]

Imagined illnesses [hypochondria]

Social phobias · Listed in decreasing order of importance.

Note MAOI is inside MelAnchOlIc.

SIADH-inducing drugs ABCD:

Analgesics: opioids, NSAIDs

Barbiturates

Cyclophosphamide/ Chlorpromazine/

Carbamazepine

Diuretic (thiazide)

K+ increasing agents K-BANK:

K-sparing diuretic

Beta blocker

ACEI

NSAID

Ksupplement

Diuretics: thiazides: indications "CHIC to use thiazides":

CHF

Hypertension

Insipidous

Calcium calculi

More Mnemonics Still to come . Keep visiting or Like the Fb page.