Eye: Corneal Dystrophies , Keratoconus


  • Corneal dystrophies are inherited as autosomal dominant  and manifest when the person is about 20 years of age.
  • They are characterized by deposits in the corneal layers.
  • Deposits in the corneal layers
  • Irregular corneal surface and corneal deposits
  • Decreased vision
  • Corneal endothelial decompensation
  • Corneal edema and blurring of vision
  • Persistent edema
  • Bullous keratopathy (formation of blisters that cause pain and discomfort on rupturing)
  • This condition is usually associated with primary open angle glaucoma.
  • A bandage contact lens is used to flatten the bullae, protect the exposed corneal nerve endings, and relieve discomfort.  
  • Symptomatic treatments-
  • Hypertonic drops or ointment (5% sodium chloride)- may reduce epithelial edema; lowering the IOP also reduces stromal edema.
  • Penetrating keratoplasty has a high success rate
  • For diffuse bullous keratopathy- amniotic membrane transplantation for patients with   limited visual ├żotential

  • Keratoconus is a condition characterized by a conical protuberance of the cornea with progressive thinning on protrusion and irregular astigmatism.
  • The hereditary condition-a higher incidence among women.
  • Onset occurs at puberty; the condition may progress for more than 20 years and is bilateral.  
  • Corneal scarring occurs in severe cases.
  • Blurred vision is a prominent symptom.
  • Rigid, gas-permeable contact lenses correct irregular astigmatism and improve vision.
  • Penetrating keratoplasty- indicated when contact lens correction is no longer effective.



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notes.nursium.com: Eye: Corneal Dystrophies , Keratoconus
Eye: Corneal Dystrophies , Keratoconus
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