· Intracellular fluid volume excess
· Occurs with acute or severe fluid volume excess.
· Results from water excess or solute deficit, primarily sodium.
· IV excessive amount of Hypo-osmolar fluids,
· Syndrome of inappropriate secretion of antidiuretic hormone.
· Hypo-osmolar fluid in the vessel move by osmosis to the region of higher concentration of sodium in the cells in an attempt to maintain equilibrium.
· Too much fluid accumulating in the cells causes cellular edema.
· Cerebral cells absorb hypo-osmolar fluid more quickly than do other cells leading to increased ICP.
THIRD SPACE FLUIDS
· Accumulation of fluid in the interstitial space.
· Results not only from pathological condition rather from inability of lymphatic system to compensate
· Increased hydrostatic pressure
· Increased capillary permeability
· Decreased serum protein level
· Obstruction o e venous portion of the capillary and nonfunctional lymphatic’s
· Are similar to hypovolemia
· Pallor, cold limbs
· Rapid pulse, hypotension
· Decreased level of consciousness.
· Body weight does not change – only fluid redistributed.
· Hypovolemic shock in severe cases.