Biochemistry Mnemonics for Medical Students This is part of best medical biochemistry mnemonics including amino acid mnemonics .These mnemonics are collected from various offline and online sources including text books.If you know any other biochemistry mnemonics please share via comments.
Essential amino acids PVT. TIM HALL:
· Pvt. is short for Private in the military.
· Arg and His are considered semiessential.
· Alternatively: “MATT VIL PHLy”.
TCA cycle substrates “Citrate Is Krebs’ Starting Substrate For Making Oxaloacetate”
Citrate, Isocitrate, alpha-Ketoglutarate, Succinyl-CoA, Succinate, Fumarate, Malate, Oxaloacetate
Start and stop codonsAUG inAUGurates transcription
UGA = U Go Away UAA = U Are Away UAG = U Are Gone
Functions of Glutathione “T. M.E.D.I.C.S”
Transport of amino acids
Erythrocyte homeostasis (inactivation of free radicals inside RBC)
Detoxification of organophosphorus, halogenated or nitrogenous compounds
Coenzyme in Reduction reactions
Scavanger of toxic substances
Catabolism steps of branched chain amino acids “Truck
hit the Ox to Death”:
Glycolysis enzymes “High Profile People
Act Too Glamorous, Picture Posing Every
Triose phosphate isomerase
Fasting state: branched-chain amino acids used by skeletal muscles
“Muscles LIVe fast”:
Creatine phosphate: amino acid precursors “Nice GAMs!”:
· Gam is slang for a person’s leg, especiallay an attractive female’s leg: “Nice
gams = nice legs!”
Trinucleotide repeat disorders”Try hunting for my fried eggs”
Trinucleotide: Huntington’s (CAG) MyoTonic dystrophy (CTG) Friedrich’s Ataxia (GAA) fraGile X syndrome (CGG)
Fabry disease: presentation FABRY:
Angiokeratomas/ Alpha galactosidase A deficiency
Porphyrias: acute intermittent porphyria symptoms 5 P’s:
Pain in abdomen
Precipitated by drugs (eg barbiturates, oral contraceptives, sulpha
BUN:creatinine elevation: causes ABCD:
Diet (high protein parenteral nutrition)
G6PD: oxidant drugs inducing hemolytic anemia AAA:
Antibiotic (eg: sufamethoxazole)
Antimalarial (eg: primaquine)
Antipyretics (eg: acetanilid, but not aspirin or acetaminophen)
Vitamin B3 (niacin, nicotinic acid) deficiency: pellagra The
3 D’s of pellagra:
· Note vitamin B3 is the 3D’s.
Glycogen storage: Anderson’s (IV) vs. Cori’s (III) enzyme defect
· Otherwise, can’t really distinguish clinically.
Benzene ring: effects of substituents on further additions
“Benzene likes to ROMP. We HOPED she’s be safe, but now she’s
knocked up. ADOPt or WEDD’M?”:
ROMP: Substituents in order: R-group, Ortho, Meta,
HOPED: Halogens are Ortho, Para, Electron
ADOPt: Addititive substituents Direct Ortho & Para.
WEDD’M: Withdrawing Electrons Deactivates, Directs
Cathode: what happens during electrolysis Current
Carries Cations to the Cathode for reduCtion.
Cis/trans (geometric) isomer nomenclature
The letter “Z” is
written in a zigzag way. If you draw a vertical line splitting it down the
middle then its the same halves (same sides of double bond). The letter “E” is
written differently so a vertical line splits it into different halves
(different sides of double bond).
Cis/trans (geometric) isomers: arrangement of functional groups
Cis starts with a C and the functional groups form a C.
Trans, therefore is the other one by default.
Pompe’s disease: type “Police = Po + lys”:
Pompe’s disease is a lysosomal storage disease (alpha 1,4
Golgi complex: functions “Golgi Distributes A SPAM”:
Distributes proteins and lipids from ER
Add mannose onto specific lysosome proteins
Sulfation of sugars and slected tyrosine
Add O-oligosugars to serine and threnonine
Modify N-ologosugars on asparagine
Dicarboxylic acids (alpha, omega) C2 through C10: common names
“Oh My, Such Good Apple Pie, Sweet