Pharmacology Mnemonics
Lupus: drugs inducing it HIP:
Hydralazine
INH
Procanimide
RTI: drugs to treat viral respiratory infections "You'd get a respiratory infection if you shoot an ARO (arrow) laced with viruses
into the lungs": ARO:
Amantadine
Rimantadine Oseltamivir
Medication administration: short checklist TRAMP: · Before dispensing medication, ensure have correct: Time
Route
Amount
Medication Patient
Opiates: overdose findings "Cool to the touch, unresponsive to
pain,
Hunger diminished, and scars over
vein.
Pupils pinpointed, and blood
pressure low,
Urine diminished, and breathing is
slow."
Lithium: side effects LITH:
Leukocytosis
Insipidus [diabetes insipidus, tied to polyuria] Tremor/ Teratogenesis Hypothyroidism
SSRIs: side effects SSRI:
Serotonin syndrome
Stimulate CNS
Reproductive disfunctions in male Insomnia
Metabolism enzyme inducers "Randy's Black Car
Goes Putt Putt and Smokes":
Rifampin
Barbiturates
Carbamazepine
Grisoefulvin
Phenytoin
Phenobarb
Smokingcigarettes
Phenobarbitone: side effects Children are annoying (hyperkinesia,
irritability, insomnia, aggression). Adults are dosy (sedation, dizziness,
drowsiness).
Cholinergics (eg organophosphates): effects If you know these, you
will be "LESS DUMB": Lacrimation
Excitation of nicotinic synapses
Salivation
Sweating
Diarrhea
Urination
Micturition
Bronchoconstriction
Routes of entry: most rapid ways meds/toxins enter body "Stick it, Sniff it, Suck it, Soak it": Stick = Injection
Sniff = inhalation
Suck = ingestion
Soak = absorption
Hepatic necrosis: drugs causing focal to massive necrosis "Very Angry Hepatocytes":
Valproic acid
Acetaminophen Halothane Warfarin: action, monitoring WePT:
Warfarin works on the extrinsic pathway and is monitored by PT.
Beta-blockers: side effects "BBC Loses Viewers In Rochedale":
Bradycardia
Bronchoconstriction
Claudication
Lipids
Vivid dreams & nightmares
-ve Inotropic action
Reduced sensitivity to hypoglycaemia
Zero order kinetics drugs (most common ones) "PEAZ
(sounds
like pees) out a constant amount": Phenytoin
Ethanol
Aspirin
Zero order · Someone that pees out a constant amount describes zero
order kinetics (always the same amount out)
Benzodiazepines: actions "Ben
SCAMs Pam into seduction not by brain but by muscle": Sedation anti-Convulsant anti-Anxiety
Muscle relaxant
Not by brain: No antipsychotic
activity.
Beta-1 vs Beta-2 receptor location "You have 1 heart and 2 lungs": Beta-1
are therefore primarily on heart.
Beta-2 primarily on lungs.
Cisplatin: major side effect, action "Ci-Splat-In": Major
side effect: Splat (vomiting
sound)--vomiting so severe that anti-nausea drug needed.
Action: Goes Into the DNA strand.
Pupils in overdose: morphine vs. amphetamine "MorPHINE: Fine. AmPHETamine: Fat": Morphine overdose: pupils constricted
(fine).
Amphetamine overdose: pupils dilated
(fat).
Atropine use: tachycardia or bradycardia "A goes with
B": Atropine used
clinically to treat Bradycardia.
Reserpine action Reserpine depletes the
Reserves of catecholamines
[and serotonin].
Botulism toxin: action, related bungarotoxin Action: "Botulism
Bottles up the Ach so it can't be the released": Related
bungarotoxin: "Botulism is
related to Beta Bungarotoxin (beta-, not alpha-bungarotoxin--alpha has different
mechanism).
Ipratropium: action Atropine
is buried in the middle: iprAtropium,
so it behaves like Atropine.
Bleomycin: action "BleoMycin
Blows My DNA to bits":
Bleomycin works by fragmenting DNA
(blowing it to bits). MyDNA signals that its used for cancer
(targeting self cells).
Propranolol and related '-olol' drugs: usage "olol" is just two backwards lower
case b's. Backward b's stand for "beta
blocker". · Beta blockers
include acebutolol, betaxolol, bisoprolol, oxprenolol,
propranolol.
Succinylcholine: action, use Succinylcholine
gets Stuck to Ach receptor, then Sucks ions in through open pore. You Suck stuff in through a mouthtube, and
drug is used for intubation.
Corticosteroids: adverse side effects CUSHINGS BAD MD:
Cataracts
Up all night (sleep disturbances)
Suppression of HPA axis
Hypertension/ buffalo Hump
Infections
Necrosis (avascular)
Gain weight
Striae
Bone loss (osteoporosis) Acne
Diabetes
Myopathy, moon faces
Depression and emotional changes
Busulfan: features ABCDEF:
Alkylating agent
Bone marrow suppression s/e
CML indication
Dark skin (hyperpigmentation) s/e
Endrocrine insufficiency (adrenal) s/e Fibrosis (pulmonary) s/e
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