Drug pheniramine maleate Action, Indication, Adverse Reactions, Contraindications & Cautions, Nursing Considerations, Patient Teaching


Pheniramine maleate
 Brand Name- Avil


Therapeutic class: Antihistamines
Pharmacologic class: Alkylamines


Competes with histamine for H1-receptor sites on effector cells. Drug prevents, but doesn’t reverse, histamine-mediated responses.


Allergic conditions
Prophylaxis of motion sickness
Allergic conjunctivitis

Adverse Reactions

CNS: drowsiness, stimulation, sedation, excitability in children.
CV: hypotension, palpitations, weak pulse.
GI: dry mouth, epigastric distress.
GU: urine retention.
Respiratory: thick bronchial secretions.
Skin: rash, urticaria, pallor.

Contraindications & Cautions

Contraindicated in patients having acute asthmatic attacks and in those with angle-closure glaucoma, symptomatic prostatic hyperplasia, pyloroduodenal obstruction, or bladder neck obstruction.
Contraindicated in patients taking MAO inhibitors.
Use cautiously in elderly patients and in those with increased IOP, hyperthyroidism, hypertension, bronchial asthma, urine retention, prostatic hyperplasia, stenosing peptic ulcerations, and CV, liver, or renal disease.

Nursing Considerations

Stop drug 4 days before diagnostic skin testing because antihistamines can prevent, reduce, or mask positive skin test response.
Monitor patient for signs and symptoms of bowel obstruction (nausea, vomiting, abdominal pain).
Monitor elderly patients for dizziness, sedation, confusion, dry mouth, constipation and hypotension.

Patient Teaching

Warn patient to avoid alcohol and hazardous activities that require alertness until CNS effects of drug are known.
Inform patient that sugarless gum, hard candy, or ice chips may relieve dry mouth.
Instruct patient to notify prescriber if tolerance develops because a different antihistamine may need to be prescribed.
Advise patient that extended-release tablets should be swallowed whole and not crushed, chewed, or divided.
Advise patient or caregiver to measure and give oral syrup by dosing syringe, dosing spoon, or dosing cup for accuracy.
May impair ability to drive or operate machinery. Has potential for abuse. Narrow angle glaucoma, asthma or severe CV disease. Antiemetic effect may mask signs of other conditions. Pregnancy and lactation. Elderly.



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notes.nursium.com: Drug pheniramine maleate Action, Indication, Adverse Reactions, Contraindications & Cautions, Nursing Considerations, Patient Teaching
Drug pheniramine maleate Action, Indication, Adverse Reactions, Contraindications & Cautions, Nursing Considerations, Patient Teaching
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